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Uptodate Reference Title
Classification of monoamine oxidase inhibitors
Classification of monoamine oxidase inhibitors
Drug
Selective*
Reversible
Isocarboxazid
No
No
Moclobemide
Yes, for MAO-A
Yes
Phenelzine
No
No
Selegiline
Yes, for MAO-B at lower doses; no at higher doses
No
Tranylcypromine
No
No
MAO-A: monoamine oxidase A; MAO-B: monoamine oxidase B. * Monoamine oxidase inhibitors differ as to whether they inhibit one or both subtypes of the enzyme monoamine oxidase. The two isomers (subtypes) are MAO-A and MAO-B.
Adapted from: Krishnan KR. Monoamine oxidase inhibitors. In: The American Psychiatric Association Publishing Textbook of Psychopharmacology, 5th edition, Schatzberg AF, Nemenoff CB (Eds), American Psychiatric Association Publishing, Arlington 2017. p.283.
