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Nociplastic pain and co-occurring pain conditions[1,2]

Nociplastic pain and co-occurring pain conditions[1,2]
  • Fibromyalgia
  • Irritable bowel syndrome
  • Tension-type headaches
  • Interstitial cystitis/pelvic pain syndrome
  • Temporomandibular joint disorder
  • Neck and back pain without structural pathology ("myofascial pain")
  • Chronic fatigue syndrome
  • Restless leg syndrome
Nociplastic pain is also known as central sensitization or pain hypersensitivity. Central sensitization plays a role in many chronic pain conditions. For further information refer to UpToDate content on chronic non-cancer pain.
References:
  1. Stanos S, Brodsky M, Argoff C, et al. Rethinking chronic pain in a primary care setting. Postgrad Med 2016; 128:502.
  2. Yunus MB. Fibromyalgia and overlapping disorders: the unifying concept of central sensitivity syndromes. Semin Arthritis Rheum 2007; 36:339.
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