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Calculator: Transferrin saturation (TSAT) in adults (conventional units)*

Calculator: Transferrin saturation (TSAT) in adults (conventional units)*

Serum iron   mcg/dL
TIBC   mcg/dL

Important: Inputs must be complete to perform calculation.

TSAT   %
Decimal precision  


  • TSAT should be evaluated in light of the clinical situation and other iron studies, especially serum ferritin. For more information, see UpToDate topics on iron overload and iron deficiency.
  • The normal range for TSAT is from 20 to 50%.
  • A high TSAT (≥45% in males or ≥40% in females) is suggestive of iron overload.
  • A low TSAT (<16% in nonpregnant adults or <20% during pregnancy) is consistent with iron deficiency.
  • TIBC: serum total iron binding capacity.
  • In this calculator, mcg is the abbreviation for micrograms.
  • * This calculator uses conventional units (also known as US units and gravimetric units) as the default for inputs. Do not use this calculator if you are using SI units (Système international d'unités); please refer instead to the SI units version of this calculator.

Equations used
TSAT = (Serum_iron / TIBC) * 100


Only digits 0 to 9 and a single decimal point (".") are acceptable as numeric inputs. Attempted input of other characters into a numeric field may lead to an incorrect result.

Information on this page may not appear correctly if printed.

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All information contained in and produced by the EBMcalc system is provided for educational purposes only. This information should not be used for the diagnosis or treatment of any health problem or disease. THIS INFORMATION IS NOT INTENDED TO REPLACE CLINICAL JUDGMENT OR GUIDE INDIVIDUAL PATIENT CARE IN ANY MANNER. Click here for full notice and disclaimer.

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