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Diagnostic criteria for classic MIRM

Diagnostic criteria for classic MIRM
Clinical and laboratory features MIRM
Skin detachment <10% BSA
Number of mucosal sites involved* ≥2
Few vesiculobullous lesions or scattered, atypical targets Yes
Targetoid lesions ±
Evidence of atypical pneumonia
  1. Clinical
Fever, cough, positive auscultatory findings
  1. Laboratory
Increase in MP IgM antibodies, MP in oropharyngeal or bullae cultures or PCR, and/or serial cold agglutinins
MIRM: Mycoplasma pneumoniae-induced rash and mucositis; BSA: body surface area; MP: Mycoplasma pneumoniae; IgM: immunoglobulin M; PCR: polymerase chain reaction.
* Rare cases have <2 mucosal sites involved.
Reproduced from: Canavan TN, Mathes EF, Frieden I, Shinkai K. Mycoplasma pneumoniae-induced rash and mucositis as a syndrome distinct from Stevens-Johnson syndrome and erythema multiforme: a systematic review. J Am Acad Dermatol 2015; 72:239. Table used with the permission of Elsevier Inc. All rights reserved.
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