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Calculator: Aspartate aminotransferase (AST) to platelet ratio index (APRI) in adults (SI units)*

Calculator: Aspartate aminotransferase (AST) to platelet ratio index (APRI) in adults (SI units)*

AST   mcKat/L
Top normal AST   mcKat/L

Important: Inputs must be complete to perform calculation.

APRI   index
Decimal precision  



APRI interpretation

APRI ≤0.3: Unlikely cirrhosis or significant fibrosis
APRI >0.3 and ≤0.5: Unlikely cirrhosis, significant fibrosis possible
APRI >0.5 and ≤1.5: Significant fibrosis or cirrhosis possible
APRI >1.5 and ≤2: Likely significant fibrosis, cirrhosis possible
APRI >2: Likely cirrhosis


  • Platelets is the platelet count.
  • The normal reference range for Platelets is approximately 150 to 400 X 109/L (SI units) [150000 to 400000/microL (conventional units)].
  • * This calculator uses SI units (Système international d'unités) as the default for inputs. Do not use this calculator if you are using conventional units (also known as US units and gravimetric units); please refer instead to the conventional units version of this calculator.

Equations used
APRI = 100 * ((AST/Top normal AST)/Platelets)


Only digits 0 to 9 and a single decimal point (".") are acceptable as numeric inputs. Attempted input of other characters into a numeric field may lead to an incorrect result.

Information on this page may not appear correctly if printed.

Legal Notices and Disclaimer

All information contained in and produced by the EBMcalc system is provided for educational purposes only. This information should not be used for the diagnosis or treatment of any health problem or disease. THIS INFORMATION IS NOT INTENDED TO REPLACE CLINICAL JUDGMENT OR GUIDE INDIVIDUAL PATIENT CARE IN ANY MANNER. Click here for full notice and disclaimer.

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