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Approach to fertility preservation for patients undergoing gonadotoxic therapy*

Approach to fertility preservation for patients undergoing gonadotoxic therapy*

* For detailed discussions of fertility preservation techniques and their application, refer to UpToDate content on ovulation induction, in vitro fertilization, and fertility preservation.

¶ Testicular cryopreservation is under investigation and not yet routinely available.

Δ In most patients, random-start protocols allow ovarian stimulation to be initiated at any time without needing to wait for menses.

◊ Choice of agent for ovarian stimulation is impacted by the type of tumor, estrogen receptor status, and presence of BRCA gene mutations.

§ While ovarian stimulation for cryopreservation of embryos or oocytes is the most established method of fertility preservation, some women may elect ovarian tissue cryopreservation instead.
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