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NCI CTCAE v5.0 osteonecrosis of the jaw

NCI CTCAE v5.0 osteonecrosis of the jaw
Adverse event Grade 1 Grade 2 Grade 3 Grade 4 Grade 5
Osteonecrosis of jaw Asymptomatic; clinical or diagnostic observations only; intervention not indicated Symptomatic; medical intervention indicated (eg, topical agents); limiting instrumental ADL Severe symptoms; limiting self-care ADL; elective operative intervention indicated Life-threatening consequences; urgent intervention indicated Death
Osteonecrosis of the jaw is characterized by a necrotic process occurring in the bone of the mandible.
NCI CTCAE: National Cancer Institute Common Terminology Criteria for Adverse Events; ADL: activities of daily living.
Reproduced from: Common Terminology Criteria for Adverse Events (CTCAE), Version 5.0, November 2017, National Institutes of Health, National Cancer Institute. Available at: https://ctep.cancer.gov/protocoldevelopment/electronic_applications/docs/CTCAE_v5_Quick_Reference_8.5x11.pdf (Accessed July 30, 2019).
Graphic 121995 Version 2.0