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Concentrations of hCG, beta-hCG, and c-beta-hCG in serum and urine of females

Concentrations of hCG, beta-hCG, and c-beta-hCG in serum and urine of females
  Median 90th percentile 97.5 percentile
<50 years ≥50 years <50 years ≥50 years <50 years ≥50 years
Serum (pmol/L)
hCG <0.8 3.7 3.4 10.6 8.6 15.5
beta-hCG <0.3 0.5 1.0 1.2 1.6 2.0
Total hCG* 0.8 4.3 4.1 11.3 9.0 17.0
Urine (pmol/L)
hCG <0.8 1.7 3.3 8.2 8.8 11.5
beta-hCG <0.3 0.6 1.0 1.8 1.7 4.3
c-beta-hCG 0.7 1.6 2.7 6.4 8.1 9.5
Total hCG* 1.8 4.6 5.5 15.4 13.6 20.4
Urine (pmol/mmol)
hCG/creatinine <0.10 0.24 0.37 0.88 0.82 1.34
beta-hCG/creatinine <0.06 0.07 0.12 0.28 0.24 0.64
c-beta-hCG/creatinine 0.07 0.23 0.21 0.93 0.51 1.25
Total hCG/creatinine* 0.20 0.63 0.78 2.06 1.31 2.92

hCG: human chorionic gonadotropin.

* Results for total hCG immunoreactivity were calculated as the sum of the concentration in individual samples.
Republished with permission of the American Association for Clinical Chemistry, from: Alfthan H, Haglund C, Dabek J, Stenman UH. Concentrations of human choriogonadotropin, its beta-subunit, and the core fragment of the beta-subunit in serum and urine of men and nonpregnant women. Clin Chem 1992; 38(10):1981; permission conveyed through Copyright Clearance Center, Inc. Copyright © American Association for Clinical Chemistry 1992. All rights reserved.
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