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Identifying HLA antibodies using single-antigen bead (SAB) testing

Identifying HLA antibodies using single-antigen bead (SAB) testing
Identifying anti-HLA antibodies using SAB testing. Shown is a representative histogram of a patient's serum reacting to multiple class I HLA antigens that are coupled to individual beads. Each histogram bar represents reactivity against a single bead, with results reported in median fluorescence intensity (MFI).
HLA: human leukocyte antigen; IgG: immunoglobulin G.
Courtesy of Melissa Y Yeung, MD, FRCPC.
Graphic 120937 Version 1.0