(Panels A and B) A typical urticarial rash on the patient's right arm.
(Panel C) Skin biopsy specimen from the left shoulder shows moderate superficial and minimal deep perivascular chronic inflammation with interstitial neutrophils and mononuclear cells (hematoxylin and eosin, original magnification ×20).
From: Shpall RL, Jeffes EW, Hoffman HM. A case of familial cold autoinflammatory syndrome confirmed by the presence of a CIAS1 mutation. Br J Dermatol 2004; 150(5):1029-31.
https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2133.2004.05927.x. Copyright © 2004 British Association of Dermatologists. Reproduced with permission of John Wiley & Sons Inc. This image has been provided by or is owned by Wiley. Further permission is needed before it can be downloaded to PowerPoint, printed, shared or emailed. Please contact Wiley's permissions department either via email:
permissions@wiley.com or use the RightsLink service by clicking on the 'Request Permission' link accompanying this article on Wiley Online Library (
https://onlinelibrary.wiley.com/).
