| Iatrogenic | - Splenic artery embolization
- Splenic irradiation
- Total or partial splenectomy
|
| Hepatic diseases | - Alcoholic liver disease
- Chronic viral hepatitis
- Cirrhosis and portal hypertension
- Primary biliary cirrhosis
|
| Hematologic diseases | - Acute leukemia
- Chronic lymphocytic leukemia
- Hematopoietic stem cell transplantation (particularly if associated graft versus host disease)
- Lymphoma
- Mastocytosis
- Myeloproliferative neoplasm
- Sickle cell disease (eg, HbSS, HbSC, HbS-beta thalassemia)
- Thalassemia
|
| Vascular impairment | - Celiac artery thrombosis
- Splenic artery thrombosis
- Splenic vein thrombosis
|
| Gastrointestinal diseases | - Celiac disease
- Inflammatory bowel disease
- Whipple's disease
|
| Autoimmune diseases | - Antiphospholipid antibody syndrome
- Goodpasture's syndrome
- Granulomatosis with polyangiitis
- Hashimoto's thyroiditis
- Polyarteritis nodosa
- Rheumatoid arthritis
- Sjogren's syndrome
- Systemic lupus erythematosus
|
| Infectious diseases | |
| Infiltrative diseases | |
| Congenital syndromes | - Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) syndrome
- Hypoparathyroidism syndrome
- Isolated congenital hyposplenia
- Ivemark's syndrome
- Normal neonatal state (particularly if birth is premature)
- Other congenital or familial syndromes
- Stormorken's syndrome
|
