Category | PEP vaccine regimen | RIG | Comments |
Category I – Touching or feeding animals, animal licks on intact skin | Not required | Not required | Exposed skin surfaces should be washed |
Category II – Nibbling of uncovered skin, minor scratches or abrasions without bleeding | Patients who have NOT been previously immunized: Immediate vaccination with one of the following regimens: - 2-sites ID on days 0, 3, and 7
- 1-site IM on days 0, 3, 7, and between days 14 and 28
- 2-sites IM on day 0 and 1-site IM on days 7 and 21
| Not required | Exposed skin surfaces should be washed |
Patients who have been previously immunized:* - 1-site ID on days 0 and 3
- 4-sites ID on day 0
- 1-site IM on days 0 and 3
| Not required | Exposed skin surfaces should be washed |
Category III – Single or multiple transdermal bites or scratches, contamination of mucous membrane or broken skin with saliva from animal licks, exposures due to direct contact with bats | Patients who have NOT been previously immunized: Immediate vaccination with one of the following regimens: - 2-sites ID on days 0, 3, and 7
- 1-site IM on days 0, 3, 7, and between days 14 and 28
- 2-sites IM on day 0 and 1-site IM on days 7 and 21
| RIG should be administered¶ | Exposed skin surfaces should be washed |
Patients who have been previously immunized:* - 1-site ID on days 0 and 3
- 4-sites ID on day 0
- 1-site IM on days 0 and 3
| Not required | Exposed skin surfaces should be washed |