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Time to hemoglobin desaturation with initial fractional alveolar oxygen concentration = 0.87

Time to hemoglobin desaturation with initial fractional alveolar oxygen concentration = 0.87
This graph shows the SaO2 versus time of apnea after maximal preoxygenation in an obese adult, a 10 kg child (low functional residual capacity [FRC] and high oxygen consumption [VO2]), and a moderately ill adult, compared with a healthy adult. The graph also shows the mean time to recovery from paralysis after a dose of succinylcholine that might be used for intubation. Critical oxygen desaturation occurs before functional recovery in most patients, even after maximal preoxygenation. 
SaO2: arterial oxyhemoglobin saturation; IV: intravenous; VE: expired volume.
From: Benumof JL, Dagg R, Benumof R. Critical hemoglobin desaturation will occur before return to unparalyzed state from 1 mg/kg succinylcholine. Anesthesiology 1997; 87:979. Copyright © 1997 American Society of Anesthesiologists. Reproduced with permission from Wolters Kluwer Health. Unauthorized reproduction of this material is prohibited.
Graphic 118559 Version 2.0