Neuroinflammation (reactive astrogliosis) in a rat model of juvenile diabetic ketoacidosis
Representative brain sections stained for GFAP (red) and NeuN (green) in the dentate gyrus region of the hippocampus. GFAP expression was significantly increased in the hippocampus during DKA, with peak values observed after 4 hours of treatment with insulin and saline.
From: Lo W, O'Donnell M, Tancredi D, et al. Diabetic ketoacidosis in juvenile rats is associated with reactive gliosis and activation of microglia in the hippocampus. Pediatr Diabetes 2016; 17(2):127-39.
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