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Calculator: PLASMIC score for estimating the likelihood of severe ADAMTS13 deficiency in adults with suspected TTP


Calculator: PLASMIC score for estimating the likelihood of severe ADAMTS13 deficiency in adults with suspected TTP

 

Platelet count <30,000/microL [<30 x 109/L]

One or more indicators of hemolysis:
      Reticulocyte count (percentage) >2.5%; or
      Haptoglobin undetectable; or
      Indirect bilirubin >2.0 mg/dL [>34 mcmol/L]

No active cancer in the preceding year

No history of solid organ or hematopoietic stem cell transplant

Mean corpuscular volume (MCV) <90 femtoliters

International normalized ratio (INR) <1.5

Creatinine <2.0 mg/dL [<177 mcmol/L]

 
Important: Inputs must be complete to perform calculation.

 
Total criteria point count:
 

 

Interpretation

 
PLASMIC score (points) Risk of severe ADAMTS13 deficiency
0 to 4 Low risk
5 Intermediate risk
6 to 7 High risk

 
Notes
  • Each criterion, if present, contributes one point to the total criteria point count. One point is added for one or more of the "Indicator of hemolysis" subcriteria, if present.
  • TTP: thrombotic thrombocytopenic purpura.
  • ADAMTS13: a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13.

 
Only digits 0 to 9 and a single decimal point (".") are acceptable as numeric inputs. Attempted input of other characters into a numeric field may lead to an incorrect result.

Information on this page may not appear correctly if printed.

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