Your activity: 151 p.v.
your limit has been reached. plz Donate us to allow your ip full access, Email: sshnevis@outlook.com

Treatment of streptococcal pharyngitis in children and adults

Treatment of streptococcal pharyngitis in children and adults
IgE: immunoglobulin E; IM: intramuscular.
* Examples of mild, non-IgE-mediated reactions include maculopapular rashes. Examples of IgE-mediated reactions include hives, wheezing, angioedema, and anaphylaxis. Examples of severe, delayed reactions include Steven-Johnson syndrome, toxic epidermal necrolysis, acute interstitial nephritis, drug-induced hepatitis, and serum sickness.
¶ Approach to selecting among cephalosporins varies among experts. Some prefer to use a first-generation cephalosporin (eg, cephalexin) because of its narrow spectrum and low likelihood of cross reactivity. Others select a third-generation cephalosporin with a side chain that is dissimilar to penicillin (eg, cefpodoxime, cefdinir), although these agents have a broader spectrum.
Δ Macrolide resistance varies considerably by region, with higher rates observed in Asia and Europe when compared with the United States. Knowledge of local resistance patterns should guide antibiotic selection.
Selection among these agents should be based on drug availability and patient preference. For patients with a history of acute rheumatic fever and penicillin allergy, antibiotic selection should be individualized.
§ Many patients with IgE-mediated reactions can tolerate cephalosporins. These patients should be referred for allergy consultation following treatment for streptococcal pharyngitis.
¥ Approach to selecting among these agents varies among experts. Some prefer cephalosporins due their high efficacy and low risk of cross-reactivity, while others favor selecting a non-cephalosporin alternative to avoid any possibility of cross-reactivity.
Graphic 115985 Version 10.0