| Findings suggesting cardiac sarcoidosis |
| Clinical findings | - LVEF <40%
- Sustained ventricular tachycardia (spontaneous or induced)
- Mobitz type II 2nd- or 3rd-degree atrioventricular block (whether or not shown to be immunosuppressant responsive)
|
| Imaging findings | - Cardiac FDG-PET with patchy focal uptake in a pattern consistent with CS
- CMR imaging with LGE in a pattern consistent with CS
|
| Diagnostic category of cardiac sarcoidosis | Criteria |
| Definite (100% probability of CS) | - Detection of noncaseating granuloma on histologic examination of myocardial tissue (endomyocardial biopsy or other myocardial specimen) with no alternative cause identified
|
| Probable (≥50% probability of CS) | - With histologic diagnosis of extracardiac sarcoidosis; requires both of the following criteria:
- 1 or more of the following types of cardiac findings:
- Clinical finding suggesting CS (refer to above)
- Imaging finding by CMR or FDG-PET typical for CS (refer to above)
- Other potential causes for the clinical and imaging findings have been excluded
|
