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Uptodate Reference Title
Our approach to the management of oral thrush in children ≥12 months
Our approach to the management of oral thrush in children ≥12 months
Predisposing factors for oral thrush in children ≥12 months include cellular immune deficiency and treatment with antibiotics, inhaled glucocorticoids, chemotherapy, or radiation therapy. Evaluation for cellular immune deficiency may be warranted for children ≥12 months who develop thrush in the absence of a predisposing factor.
HIV: human immunodeficiency virus; IV: intravenous. * Nystatin solution should be swished and held in the mouth as long as possible before being swallowed. ¶ Lozenges should not be used in children younger than four years. Δ IV fluconazole may be warranted for immunocompromised children with thrush and oropharyngeal pain that interferes with eating. ◊ Fluconazole-resistant Candida may be suspected in children who are known to be colonized with a resistant species (eg, Candida glabrata, Candida krusei), children who have been receiving azole antifungal prophylaxis, and children cared for in medical centers with a high proportion of resistant species. § Refer to Lexicomp monograph for dosing.
