Society guideline links: Male infertility or hypogonadism

Introduction — This topic includes links to society and government-sponsored guidelines from selected countries and regions around the world. We will update these links periodically; newer versions of some guidelines may be available on each society's website. Some societies may require users to log in to access their guidelines.

The recommendations in the following guidelines may vary from those that appear in UpToDate topic reviews. Readers who are looking for UpToDate topic reviews should use the UpToDate search box to find the relevant content.

Links to related guidelines are provided separately. (See "Society guideline links: Testosterone therapy in men" and "Society guideline links: Male sexual dysfunction".)

International

●Endocrine Society (ES): Clinical practice guideline on testosterone therapy in men with hypogonadism (2018)

●International Late Effects of Childhood Cancer Guideline Harmonization Group (IGHG) and the PanCare Childhood and Adolescent Cancer Survivor Care and Follow-Up Studies (PanCareSurFup) Consortium: Recommendations for gonadotoxicity surveillance in male childhood, adolescent, and young adult cancer survivors (2017)

●International Society For The Study of the Aging Male (ISSAM): Recommendations on the diagnosis, treatment and monitoring of hypogonadism in men (2015)

Canada

●Choosing Wisely Canada: Don't order serum testosterone in men without symptoms of hypogonadism (updated 2020)

●Choosing Wisely Canada: Don't routinely perform sperm DNA fragmentation testing (updated 2020)

●Canadian Men's Health Foundation (CMHF): Diagnosis and management of testosterone deficiency syndrome in men: Clinical practice guideline (2015)

United States

●American Society for Reproductive Medicine (ASRM): Ethics committee opinions and webinars

●ASRM: Evidence-based treatments for couples with unexplained infertility – A guideline (2020)

●ASRM: Fertility preservation in patients undergoing gonadotoxic therapy or gonadectomy – A committee opinion (2019)

●ASRM: The management of obstructive azoospermia – A committee opinion (2019)

●American Society of Clinical Oncology (ASCO): Clinical practice guideline on fertility preservation in patients with cancer (2018)

●American Urological Association (AUA): Guidelines for the evaluation and management of testosterone deficiency (2018)

●ASRM: Diagnostic evaluation of sexual dysfunction in the male partner in the setting of infertility – A committee opinion (2018)

●ASRM: Evaluation of the azoospermic male – A committee opinion (2018)

●ASRM: Management of nonobstructive azoospermia – A committee opinion (2018)

●ASRM: Smoking and infertility – A committee opinion (2018)

●ASRM: Diagnostic evaluation of the infertile male – A committee opinion (2015)

●ASRM: Obesity and reproduction – A committee opinion (2015)

●Choosing Wisely: Don't prescribe testosterone or testosterone products to men contemplating/attempting to initiate pregnancy (2015)

●US Food and Drug Administration (FDA): Testosterone information (updated 2015)

●ASRM and Society for Male Reproduction and Urology (SMRU): Report on varicocele and infertility – A committee opinion (2014)

●ASRM: Recommendations for reducing the risk of viral transmission during fertility treatment with the use of autologous gametes – A committee opinion (2013)

●ASRM: The clinical utility of sperm DNA integrity testing – A guideline (2013)

●Choosing Wisely: Don't perform a postcoital test (PCT) for the evaluation of infertility (2013)

●Choosing Wisely: Don't perform immunological testing as part of the routine infertility evaluation (2013)

●Choosing Wisely: Don't prescribe testosterone therapy unless there is biochemical evidence of testosterone deficiency (2013)

●Choosing Wisely: Don't routinely order thrombophilia testing on patients undergoing a routine infertility evaluation (2013)

●ASRM and Society for Assisted Reproductive Technology (SART): Intracytoplasmic sperm injection (ICSI) for non-male factor infertility – A committee opinion (2012)

Europe

●European Academy of Andrology (EAA): Guidelines on Klinefelter syndrome (2021)

●European Society of Urogenital Radiology (ESUR): Ultrasound evaluation of varicoceles – Guidelines and recommendations for detection, classification, and grading (2020)

●EAA: Guideline – Management of oligo-astheno-teratozoospermia (2018)

●European Association of Urology (EAU): Guidelines on sexual and reproductive health (2018)

●European consensus statement on congenital hypogonadotropic hypogonadism – Pathogenesis, diagnosis and treatment (2015)

●EAA and European Molecular Genetics Quality Network (EMQN): Best practice guidelines for molecular diagnosis of Y-chromosomal microdeletions – State-of-the-art 2013 (published 2014)

●European Menopause and Andropause Society (EMAS): Position statement on fertility preservation (2014)

United Kingdom

●National Institute for Health and Care Excellence (NICE): Clinical guideline on fertility problems – Assessment and treatment (2013, updated 2017)

●NICE: Quality standard on fertility problems (2014)

●Scottish Intercollegiate Guidelines Network (SIGN): Long term follow up of survivors of childhood cancer (2013)

Australia-New Zealand

●Choosing Wisely Australia: Don't prescribe testosterone therapy unless there is evidence of proven testosterone deficiency

●Endocrine Society of Australia (ESA): Position statement on male hypogonadism (part 1) – Assessment and indications for testosterone therapy (2016)

●ESA: Position statement on male hypogonadism (part 2) – Treatment and therapeutic considerations (2016)

Japan

●Japanese Cancer Therapy Society (JCTS): Medical practice guidelines for preserving fertility in children, adolescents and young cancer patients (2017)

●The Japanese Urological Association (JUA)/Japanese Society for the Study of the Aging Male (JSSAM): Clinical practice manual for late-onset hypogonadism syndrome (2008)