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Calculator: Splenic Marginal Zone Lymphoma Study Group (SMZLSG) prognostic index in adults

Calculator: Splenic Marginal Zone Lymphoma Study Group (SMZLSG) prognostic index in adults

LDH score LDH normal (0)

LDH high (1)
LAD score Extrahilar adenopathy absent (0)

Extrahilar adenopathy present (1)

Important: Inputs must be complete to perform calculation.

Prognostic index   index
Decimal precision  




SMZLSG prognostic index Risk category 5-year survival*
Derivation cohort
5-year survival*
Validation cohort
≥2.6 Low risk 94% 96%
≥0.9 and <2.6 Intermediate risk 78% 88%
<0.9 High risk 69% 44%


  • *Lymphoma-specific survival at 5 years.
  • LDH: lactate dehydrogenase; LAD: lymphadenopathy.

Equations used
Prognostic_index = (0.2 * Hemoglobin) + (0.006 * Platelets) - LDH_score - LAD_score


Equation parameters, such as LDH score, have two or more discrete values that may be used in the calculation. The numbers in the parentheses, eg, (0), represent the values that will be used.

Only digits 0 to 9 and a single decimal point (".") are acceptable as numeric inputs. Attempted input of other characters into a numeric field may lead to an incorrect result.

Information on this page may not appear correctly if printed.

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