| Medical condition |
| General |
| Normal activity inhibited |
| Monitoring or medical assistance at home within two months |
| Hospital admission within two months |
| Obesity (BMI >40 kg/m2) |
| Frailty |
| Malnourishment |
| Cardiovascular |
| Coronary artery disease |
| Arrhythmias |
| Systolic blood pressure >160 mmHg or diastolic blood pressure >100 mmHg |
| Heart failure |
| Respiratory |
| Asthma, severe |
| COPD with symptoms |
| Exacerbation or progression of COPD or asthma within two months |
| Previous airway surgery |
| Unusual airway anatomy |
| Airway tumor or obstruction |
| Home ventilatory assistance or monitoring |
| OSA without PAP therapy |
| Endocrine |
| Diabetes requiring insulin therapy |
| Adrenal disorders |
| Active thyroid disease |
| Central nervous system/Neuromuscular |
| Seizure disorder |
| CNS disease (eg, multiple sclerosis) |
| Myopathy or other muscle disorders |
| Hepatic |
| Active hepatobiliary disease or compromise |
| Renal |
| Renal insufficiency or failure |
| Musculoskeletal |
| Kyphosis or scoliosis compromising function |
| Temporomandibular joint disorder limiting mouth opening |
| Cervical or thoracic spine injury/disease |
| Oncology |
| Chemo- or radiotherapy within last two months |
| Significant physiologic compromise from disease or treatment |
