MAC is the minimum alveolar concentration of an inhalation anesthetic agent that prevents 50% of patients from moving in response to a surgical stimulus. MAC is lowest in the extreme elderly: data are for ages 5 to 95 years.
Data from:
- Cameron CB, Robinson S, Gregory GA. The minimum alveolar concentration of Isoflurane in children. Anesth Analg 1984; 63:418.
- Stevens WC, Dolan WM, Gibbons RT, et al. Minimum alveolar concentrations (MAC) of isoflurane with and without nitrous oxide in patients of various ages. Anesthesiology 1975; 42:197.
From: LeDez KM, Lerman J. The minimum alveolar concentration (MAC) of isoflurane in preterm neonates. Anesthesiology 1987; 67:301. Copyright © 1987 American Society of Anesthesiologists. Reproduced with permission from Wolters Kluwer Health. Unauthorized reproduction of this material is prohibited.
