Estimated glomerular filtration rate (eGFR) over time during follow-up in SPRINT participants with chronic kidney disease (CKD)

Two phases of eGFR changes during follow-up in the SPRINT participants with CKD. The rate of change in eGFR using the values at 6 months after randomization as the baseline was -0.47 mL/minute/1.73 m² per year in the intensive group (dashed line and triangles) and -0.32 mL/minute/1.73 m² per year in the standard group (solid line and circles). Open symbols denote fasting visits; closed symbols denote nonfasting visits.