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Uptodate Reference Title
Main MRI changes in CADASIL
Main MRI changes in CADASIL
(A) Lacunar infarcts shown on T1-weighted imaging are mainly located in the brainstem (pons), thalamus, and lentiform nuclei in a 61-year-old man with a history of stroke, gait difficulties, and executive dysfunction with memory deficits. (B) Small deep infarcts are shown on fluid-attenuated inversion recovery images in association with diffuse and confluent white-matter hyperintensities involving the anterior part of the temporal lobes. (C) Microbleeds are visible on T2 or gradient-echo images as small hypointense foci in the thalamus and brainstem.
CADASIL: cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.
Reproduced from: Chabriat H, Joutel A, Dichgans M, et al. Cadasil. Lancet Neurol 2009; 8:643. Illustration used with the permission of Elsevier Inc. All rights reserved.
