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The effect of the C-to-T transition in exon 7 between SMN1 and SMN2 on splicing

The effect of the C-to-T transition in exon 7 between SMN1 and SMN2 on splicing
SMN1: survival motor neuron 1 gene; SMN2: survival motor neuron 2 gene.
Original figure modified for this publication. Butchbach ME, Burghes AH. Perspectives on models of spinal muscular atrophy for drug discovery. Drug Discov Today Dis Models 2004; 1:151. Illustration used with the permission of Elsevier Inc. All rights reserved. From: Butchbach ME. Copy Number Variations in the Survival Motor Neuron Genes: Implications for Spinal Muscular Atrophy and Other Neurodegenerative Diseases. Front Mol Biosci 2016; 3:7. Copyright © 2016 Butchbach. Available at: http://journal.frontiersin.org/article/10.3389/fmolb.2016.00007/full (Accessed March 27, 2017). Reproduced under the terms of the Creative Commons Attribution License.
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