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MGRS lesions with organized deposits

MGRS lesions with organized deposits
(A) Randomly arranged solid fibrillar deposits (diameter of 8 to 12 nm) in AL amyloidosis.
(B) Microtubular deposits (diameter of 17 to 52 nm), characterized by their hollow center, in immunotactoid glomerulopathy. They are commonly arranged in parallel arrays.
(C) Intracellular needle and rhomboid-shaped crystalline inclusions in light chain proximal tubulopathy.
MGRS: monoclonal gammopathy of renal significance; AL: immunoglobulin light chain.
Courtesy of Samih H Nasr, MD, College of Medicine, Mayo Clinic.
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