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Emergencies associated with pancytopenia

Emergencies associated with pancytopenia
  • Neutropenia (new diagnosis or associated with fever/infection)
  • Symptomatic anemia (eg, cardiac ischemia, hemodynamic instability, worsening congestive heart failure)
  • Thrombocytopenia (platelets <10,000/microL, or <50,000/microL associated with bleeding)
  • Disseminated intravascular coagulation
  • Abnormal peripheral blood smear (eg, microangiopathy, blasts)
  • Severe aplastic anemia
  • Hemophagocytic lymphohistiocytosis
  • Metabolic emergencies (eg, symptomatic hypercalcemia, hyperkalemia, tumor lysis syndrome)
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