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Sequence of events in a hemolytic transfusion reaction

Sequence of events in a hemolytic transfusion reaction
This schematic shows the sequence of immunologic events involved in a hemolytic transfusion reaction (HTR). Refer to UpToDate for further information on the pathophysiology and clinical presentation of acute and delayed HTRs.
TNF-alpha: Tumor necrosis factor alpha.
Reproduced from: Davenport RD. Pathophysiology of Hemolytic Transfusion Reactions. Semin Hematol 2005; 42:165. Illustration used with the permission of Elsevier Inc. All rights reserved.
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