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Uptodate Reference Title
Normal levels of folic acid in pregnancy
Normal levels of folic acid in pregnancy
Nutrient
First trimester
Second trimester
Third trimester
Folate, serum (ng/mL)
2.6 to 15.0
0.8 to 24.0
1.4 to 20.7
Folate, red blood cell (ng/mL)
137 to 589
94 to 828
109 to 663
NOTE: The World Health Organization recommends a minimum red blood cell folate level of 400 ng/mL prior to conception and in the first trimester.
Data from: Abbassi-Ghanavati M, Greer LG, Cunningham FG. Pregnancy and laboratory studies: A reference table for clinicians. Obstet Gynecol 2009; 114:1326.
