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Uptodate Reference Title
5- and 10-year disease-free survival (DFS) according to posttreatment pathologic (yp) stage and tumor regression grade (TRG) at resection after neoadjuvant chemoradiotherapy in the German Rectal Cancer Study Group (CAO/ARO/AIO-94) trial
5- and 10-year disease-free survival (DFS) according to posttreatment pathologic (yp) stage and tumor regression grade (TRG) at resection after neoadjuvant chemoradiotherapy in the German Rectal Cancer Study Group (CAO/ARO/AIO-94) trial
yp category
5-year DFS (%)
10-year DFS (%)
ypT
T0
86
90
T1
95
95
T2
81
78
T3
65
66
T4
42
40
ypN
N0
85
84
N1
65
59
N2
18
28
TRG
5-year DFS (%)
10-year DFS (%)
4
86
90
2-3
75
74
0-1
63
63
Five-tier system for TRG. Complete regression = TRG 4; intermediate regression = TRG 2-3; poor or no regression = TRG 0-1.
Data from: Rödel C, Martus P, Papadoupolos T, et al. Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer. J Clin Oncol 2005; 23:8688 and Fokas E, Liersch T, Fietkau R, et al. Tumor regression grading after preoperative chemoradiotherapy for locally advanced rectal carcinoma revisited: updated results of the CAO/ARO/AIO-94 trial. J Clin Oncol 2014; 32:1554.