| Systolic blood pressure ≥160 mmHg or diastolic blood pressure ≥110 mmHg, or both (on two separate occasions) |
| Symptoms of central nervous system dysfunction: |
New-onset cerebral or visual disturbance, such as: - Photopsia, scotomata, cortical blindness, retinal vasospasm
- Severe headache (ie, incapacitating, "the worst headache I've ever had") or headache that persists and progresses despite analgesic therapy
|
| Hepatic abnormality: |
| Severe persistent right upper quadrant or epigastric pain unresponsive to medication and not accounted for by an alternative diagnosis or serum transaminase concentration ≥2 times the upper limit of the normal range, or both |
| Thrombocytopenia: |
| <100,000 platelets/microL |
| Renal abnormality: |
| Progressive renal insufficiency (serum creatinine >1.1 mg/dL [97.2 micromol/L] or doubling of serum creatinine concentration in the absence of other renal disease) |
