Primary tumor (T) |
T category | T criteria |
TX | Primary tumor cannot be assessed |
Tis | Carcinoma in situ/high-grade dysplasia |
T1 | Tumor invades the bile duct wall with a depth less than 5 mm |
T2 | Tumor invades the bile duct wall with a depth of 5 to 12 mm |
T3 | Tumor invades the bile duct wall with a depth greater than 12 mm |
T4 | Tumor involves the celiac axis, superior mesenteric artery, and/or common hepatic artery |
Regional lymph nodes (N) |
N category | N criteria |
NX | Regional lymph nodes cannot be assessed |
N0 | No regional lymph node metastasis |
N1 | Metastasis in one to three regional lymph nodes |
N2 | Metastasis in four or more regional lymph nodes |
Distant metastasis (M) |
M category | M criteria |
M0 | No distant metastasis |
M1 | Distant metastasis |
Prognostic stage groups |
When T is... | And N is... | And M is... | Then the stage group is... |
Tis | N0 | M0 | 0 |
T1 | N0 | M0 | I |
T1 | N1 | M0 | IIA |
T1 | N2 | M0 | IIIA |
T2 | N0 | M0 | IIA |
T2 | N1 | M0 | IIB |
T2 | N2 | M0 | IIIA |
T3 | N0 | M0 | IIB |
T3 | N1 | M0 | IIB |
T3 | N2 | M0 | IIIA |
T4 | N0 | M0 | IIIB |
T4 | N1 | M0 | IIIB |
T4 | N2 | M0 | IIIB |
Any T | Any N | M1 | IV |