Primary tumor (T) |
Male penile urethra and female urethra |
T category | T criteria |
TX | Primary tumor cannot be assessed |
T0 | No evidence of primary tumor |
Ta | Non-invasive papillary carcinoma |
Tis | Carcinoma in situ |
T1 | Tumor invades subepithelial connective tissue |
T2 | Tumor invades any of the following: Corpus spongiosum, periurethral muscle |
T3 | Tumor invades any of the following: Corpus cavernosum, anterior vagina |
T4 | Tumor invades other adjacent organs (eg, invasion of the bladder wall) |
Prostatic urethra |
T category | T criteria |
TX | Primary tumor cannot be assessed |
T0 | No evidence of primary tumor |
Ta | Non-invasive papillary carcinoma |
Tis | Carcinoma in situ involving the prostatic urethra or periurethral or prostatic ducts without stromal invasion |
T1 | Tumor invades urethral subepithelial connective tissue immediately underlying the urothelium |
T2 | Tumor invades the prostatic stroma surrounding ducts either by direct extension from the urothelial surface or by invasion from prostatic ducts |
T3 | Tumor invades the periprostatic fat |
T4 | Tumor invades other adjacent organs (eg, extraprostatic invasion of the bladder wall, rectal wall) |
Regional lymph nodes (N) |
N category | N criteria |
NX | Regional lymph nodes cannot be assessed |
N0 | No regional lymph node metastasis |
N1 | Single regional lymph node metastasis in the inguinal region or true pelvis (perivesical, obturator, internal [hypogastric] and external iliac), or presacral lymph node |
N2 | Multiple regional lymph node metastasis in the inguinal region or true pelvis (perivesical, obturator, internal [hypogastric] and external iliac), or presacral lymph node |
Distant metastasis (M) |
M category | M criteria |
M0 | No distant metastasis |
M1 | Distant metastasis |
Prognostic stage groups |
When T is... | And N is... | And M is... | Then the stage group is... |
Tis | N0 | M0 | 0is |
Ta | N0 | M0 | 0a |
T1 | N0 | M0 | I |
T1 | N1 | M0 | III |
T2 | N0 | M0 | II |
T2 | N1 | M0 | III |
T3 | N0 | M0 | III |
T3 | N1 | M0 | III |
T4 | N0 | M0 | IV |
T4 | N1 | M0 | IV |
Any T | N2 | M0 | IV |
Any T | Any N | M1 | IV |