Primary tumor (T) |
T category | T criteria |
TX | Primary tumor cannot be assessed |
T0 | No evidence of primary tumor |
Ta | Noninvasive papillary carcinoma |
Tis | Urothelial carcinoma in situ: "Flat tumor" |
T1 | Tumor invades lamina propria (subepithelial connective tissue) |
T2 | Tumor invades muscularis propria |
pT2a | Tumor invades superficial muscularis propria (inner half) |
pT2b | Tumor invades deep muscularis propria (outer half) |
T3 | Tumor invades perivesical soft tissue |
pT3a | Microscopically |
pT3b | Macroscopically (extravesical mass) |
T4 | Extravesical tumor directly invades any of the following: Prostatic stroma, seminal vesicles, uterus, vagina, pelvic wall, abdominal wall |
T4a | Extravesical tumor invades directly into prostatic stroma, seminal vesicles, uterus, vagina |
T4b | Extravesical tumor invades pelvic wall, abdominal wall |
Regional lymph nodes (N) |
N category | N criteria |
NX | Lymph nodes cannot be assessed |
N0 | No lymph node metastasis |
N1 | Single regional lymph node metastasis in the true pelvis (perivesical, obturator, internal and external iliac, or sacral lymph node) |
N2 | Multiple regional lymph node metastasis in the true pelvis (perivesical, obturator, internal and external iliac, or sacral lymph node metastasis) |
N3 | Lymph node metastasis to the common iliac lymph nodes |
Distant metastasis (M) |
M category | M criteria |
M0 | No distant metastasis |
M1 | Distant metastasis |
M1a | Distant metastasis limited to lymph nodes beyond the common iliacs |
M1b | Non-lymph-node distant metastases |
Prognostic stage groups |
When T is... | And N is... | And M is... | Then the stage group is... |
Ta | N0 | M0 | 0a |
Tis | N0 | M0 | 0is |
T1 | N0 | M0 | I |
T2a | N0 | M0 | II |
T2b | N0 | M0 | II |
T3a, T3b, T4a | N0 | M0 | IIIA |
T1-T4a | N1 | M0 | IIIA |
T1-T4a | N2, N3 | M0 | IIIB |
T4b | Any N | M0 | IVA |
Any T | Any N | M1a | IVA |
Any T | Any N | M1b | IVB |