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Erythema nodosum
Erythema nodosum
(A) Septal panniculitis with mixed inflammatory infiltrate containing histiocytes, lymphocytes, neutrophils, and eosinophils.
(B) Meischer's radial granulomas (small, nodular aggregates of histiocytes surrounding "banana-shaped" extracellular clefts). Neutrophils surround the granulomas.
(C) Multinucleated giant cells (a feature of late-stage erythema nodosum).
(D) Septal inflammation with eosinophils, sparing the adipocytes.
Courtesy of Alireza Sepehr, MD.
Graphic 110243 Version 1.0