Rapid attainment of steady state with remifentanil
Rapid attainment of steady state with remifentanil
Simulation demonstrating plasma concentrations after administration of a bolus dose of remifentanil followed by an infusion, showing the rapid attainment of steady state when a bolus is used.
Ce: Effect site concentration.
Reproduced from: Ogura T, Egan TD. Opioid Agonists and Antagonists. In: Pharmacologyand Physiology for Anesthesia: Foundations and Clinical Application, Hemmings HC, Egan TD (Eds), Philadelphia, PA, Elsevier, 2013. Illustration used with the permission of Elsevier Inc. All rights reserved.
