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PCSK9 pathway and effect of PCSK9 antibody on LDL-R

PCSK9 pathway and effect of PCSK9 antibody on LDL-R
LDL-R: low density lipoprotein cholesterol receptor.
Reprinted by permission from Macmillan Publishers Ltd: Nature Reviews Drug Discovery. Mullard A. Cholesterol-lowering blockbuster candidates speed into Phase III trials. Nat Rev Drug Discov 2012; 11:817. Copyright © 2012. www.nature.com/nrd.
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