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Blistering skin changes on the hand of an individual with variegate porphyria

Blistering skin changes on the hand of an individual with variegate porphyria
The hand of a patient with variegate porphyria shows blisters, premature ageing, and changes in pigmentation.
Reproduced with permission from: Hift RJ, Peters TJ, Meissner PN. A review of the clinical presentation, natural history and inheritance of variegate porphyria: its implausibility as the source of the 'Royal Malady'. J Clin Pathol 2012; 65(3):200-5. Copyright © 2012 BMJ Publishing Group Ltd.
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