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Uptodate Reference Title
Drugs used for neuraxial labor analgesia
Drugs used for neuraxial labor analgesia
Epidural*
Spinal
Local anesthetic
Bupivacaine
0.0625 to 0.1%
2.5 to 5 mg alone
2 to 3 mg with opioid
Ropivacaine
0.08 to 0.2%
3 to 4 mg alone
2 to 4 mg with opioid
Opioid
Fentanyl
1 to 3 mcg/mL
15 to 25 mcg alone
10 to 15 mcg with LA
Sufentanil
0.2 to 0.5 mcg/mL
5 to 8 mcg alone
2.5 to 5 mcg with LA
LA: local anesthetic. * Epidural analgesia is initiated with a bolus of 10 to 20 mL of a combination of an LA (either bupivacaine or ropivacaine, with or without a 3-mL lidocaine with epinephrine test dose) and an opioid (either fentanyl or sufentanil). Epidural analgesia is maintained with the same or a more dilute solution, administered by infusion and patient-controlled epidural analgesia.
