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Evaluating CVD risk in females contemplating MHT

Evaluating CVD risk in females contemplating MHT
10-year CVD risk Years since menopause onset
<10 years
Low (<5%) MHT ok
Moderate (5 to 10%) MHT ok (choose transdermal)
High (>10%)* Avoid MHT
CVD risk calculated by ACC/AHA Cardiovascular Risk Calculator. Methods to calculate risk and risk stratification vary among countries.

CVD: cardiovascular disease; MHT: menopausal hormone therapy; ACC: American College of Cardiology; AHA: American Heart Association.

* High risk includes known myocardial infarction (MI), stroke, peripheral artery disease, etc.
Adapted from:
  1. Manson JE. Current recommendations: what is the clinician to do? Fertil Steril 2014; 101:916.
  2. Stuenkel CA, Davis SR, Gompel A, et al. Treatment of symptoms of the menopause: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2015; 100:3975.
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