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Uptodate Reference Title
ISUP grade group classification system
ISUP grade group classification system
Grade group
Gleason score and pattern
1
Grade 6 (3+3)
2
Grade 7 (3+4)
3
Grade 7 (4+3)
4
Grade 8 (4+4, 3+5, or 5+3)
5
Grade 9 or 10 (4+5, 5+4, or 5+5)
ISUP: International Society of Urological Pathology.
Adapted from: Epstein JI, Egevad L, Amin MB, et al. The 2014 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma: Definition of Grading Patterns and Proposal for a New Grading System. Am J Surg Pathol 2016; 40:244.
