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Advantages and disadvantages of the primary treatment approaches for early prostate cancer

Advantages and disadvantages of the primary treatment approaches for early prostate cancer
Treatment Advantages Disadvantages
Prostatectomy
  • Possibility of permanently curing your cancer
  • If your doctor needs to remove lymph nodes for testing, this can be done during the same surgery
  • Risk of erectile dysfunction or urinary incontinence
  • Risk of complications associated with any surgical procedure (such as bleeding, pain, or infection)
  • Requires time to recover before returning to work/activities
External beam radiation therapy
  • Possibility of permanently curing your cancer
  • You can continue your normal activities during treatment
  • Side effects may include erectile dysfunction, needing to urinate urgently, urinary incontinence, bladder pain, or proctitis (swelling and pain in the rectum)
  • Requires committing to treatment 5 days a week for 4 to 8 weeks
Brachytherapy
  • Possibility of permanently curing your cancer
  • Unlike external beam radiation therapy, usually only requires 1 treatment session
  • Requires anesthesia to have the radiation-emitting device(s) implanted
  • Side effects may include erectile dysfunction, urinary urgency and frequency, burning with urination, or trouble emptying the bladder
  • Less common side effects include bowel urgency and frequency, rectal bleeding, and rectal ulcers
Active surveillance
  • Avoids or delays all risks and side effects associated with treatment
  • The cancer could grow or spread, making it harder to treat and maybe impossible to cure; however, men are generally closely monitored with blood tests, examinations, X-rays, and/or prostate biopsies in order to detect any increase in the risk of cancer growth and spread (in which case definitive treatment can be offered)
  • Knowing that you have cancer but aren't treating it might cause stress or anxiety
Reference:
  1. Vogelzang NJ, Scardino PT, Shipley WU, et al. Comprehensive textbook of genitourinary oncology, 3rd Ed, Lippincott Williams & Wilkins, Philadelphia 2005.
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