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Uptodate Reference Title
Advantages and disadvantages of oral versus IV iron
Advantages and disadvantages of oral versus IV iron
Advantages
Disadvantages
Oral iron
Effective for most patients
Extremely low risk of serious adverse events
Initial costs very low
Gastrointestinal side effects are common
Compliance may be low
May be inadequate for severe or ongoing blood loss
May require administration for several months
Total costs may be higher
IV iron
Effective for most patients
More rapid correction of anemia and resolution of symptoms
Ability to administer large doses (up to 1000 mg elemental iron) in a single infusion
Compliance is assured
No gastrointestinal side effects
Requires monitored intravenous infusion
Rare cases of allergic or infusion reactions
Requires equipment and personnel to treat allergic or infusion reactions
Initial costs may be higher
Refer to UpToDate content on the management of iron deficiency for further details. Advantages, disadvantages, costs, and burdens for any individual patient may depend on a number of factors.
