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Hemodynamic definitions of pre- and post-capillary pulmonary hypertension

Hemodynamic definitions of pre- and post-capillary pulmonary hypertension
Definitions Characteristics Clinical groups*
Pre-capillary PH

mPAP >20 mmHg

PAWP ≤15 mmHg

PVR ≥3 WU		 1, 3, 4, and 5
Isolated post-capillary PH (IpcPH)

mPAP >20 mmHg

PAWP >15 mmHg

PVR <3 WU		 2 and 5
Combined pre- and post-capillary PH (CpcPH)

mPAP >20 mmHg

PAWP >15 mmHg

PVR ≥3 WU		 2 and 5
PH: pulmonary hypertension; mPAP: mean pulmonary arterial pressure; PAWP: pulmonary arterial wedge pressure; PVR: pulmonary vascular resistance; WU: Wood units.
* Group 1: PAH; group 2: PH due to left heart disease; group 3: PH due to lung diseases and/or hypoxia; group 4: PH due to pulmonary artery obstructions; group 5: PH with unclear and/or multifactorial mechanisms.
Reproduced with permission of the © ERS 2019: European Respiratory Journal 53 (1) 1801913; DOI: 10.1183/13993003.01913-2018. Published 24 January 2019.
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