Living in geographic regions with rates of penicillin-nonsusceptible S. pneumonia exceeding 10%* |
Age ≥65 years |
Hospitalization in the last 5 days |
Antibiotic use in the previous month |
Immunocompromise |
Multiple comorbidities (eg, diabetes or chronic cardiac, hepatic, or renal disease) |
Severe infection (eg, evidence of systemic toxicity with temperature of ≥102°F, threat of suppurative complications) |