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Low-density lipoprotein cholesterol levels and genetic mutations in familial hypercholesterolemia

Low-density lipoprotein cholesterol levels and genetic mutations in familial hypercholesterolemia
LDL-C units are mg/dL; divide by 38.67 to convert to mmol/L.
LDL-C: low-density lipoprotein cholesterol; FH: familial hypercholesterolemia; LDLR: LDL receptor gene; APOB: apolipoprotein B gene; PCSK9: proprotein convertase subtilisin kexin 9.
Adapted from: Cuchel M, Bruckert E, Ginsberg HN, et al. Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society. Eur Heart J 2014; 35:2146.
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