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Survival in double hit and double expressor diffuse large B cell lymphoma

Survival in double hit and double expressor diffuse large B cell lymphoma
Overall survival in 307 patients with diffuse large B cell lymphoma according to molecular subtype. Double hit lymphoma (DHIT) were those that had translocations of MYC and BCL2. The MYC+/BCL2+ lymphoma subgroup included those that expressed both MYC and BCL2 on immunohistochemistry and excluded those meeting the requirements for DHIT. Four DHIT patient cases had no MYC protein expression; one had a missing value for BCL2 protein expression.
From: Johnson NA, Slack GW, Savage KJ, et al. Concurrent expression of MYC and BCL2 in diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone. J Clin Oncol 2012; 30(28):3452-9. Reprinted with permission. Copyright © 2012 American Society of Clinical Oncology. All rights reserved.
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