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Complex movements during sleep: Distinguishing clinical features

Complex movements during sleep: Distinguishing clinical features
  Disorders of arousal Sleep-related eating disorder REM sleep behavior disorder REM nightmares Recurrent isolated sleep paralysis Psychiatric events Nocturnal seizures
Behavior Confused, semi-purposeful movement with eyes open Eating high caloric or unusual foods with eyes open Sometimes combative, violent dream enactment with eyes closed Vivid, disturbing dreams, may end with a sudden jolt or jerk Inability to move with preservation of eye and diaphragmatic movement Variable, may involve panic or dissociative symptoms Dependent on location of epileptic focus; may be brief jerks, simple or complex stereotypical behavior
Age of onset Childhood or adolescence Variable Older adults Childhood or adulthood Variable Adolescence to adulthood Variable
Family history Yes Unknown No No No No Variable
Time of occurrence First third of night First half of night During REM sleep Second half of the night most common (during REM sleep) Upon awakening Any time Any time, but more likely in first half of night
Frequency Once per night but not every night Variable Variable; a few times per month to nightly May be nightly Variable, less than weekly Variable Frontal lobe seizure can occur multiple times per night; less often for temporal lobe seizures
Duration Minutes Minutes Seconds to a minute Movement lasts seconds Seconds to a minute Variable (usually minutes or longer) Usually less than 3 minutes
Memory of event Usually none Usually none, or limited Fragmentary to full dream recall Yes Yes None Variable
Stereotypical movements No No No No No No Yes
PSG findings Arousals from slow-wave sleep Arousal from NREM sleep Excessive EMG tone during REM sleep Awakening out of REM sleep appearing distressed Arousal from REM sleep Occur from wake state Epileptiform activity
Associated clinical findings May indicate another problem causing arousals (eg, sleep apnea) Morning anorexia, unexplained weight gain, comorbid RLS May be associated with parkinsonism, narcolepsy, or medications (antidepressants) May be associated with stress, psychological trauma, or medication effect None (benign) Other features of an underlying psychiatric disorder (eg, panic, anxiety, depression) May find focal neurologic deficits
REM: rapid eye movement; PSG: polysomnogram; NREM: non-REM; EMG: electromyography; RLS: restless legs syndrome.
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