| Estimated risk¶ |
Prematurity |
GA <28 weeks | OR 60.9, 95% CI 34.3-108.0 |
GA 28 to 31 weeks | OR 32.0, 95% CI 20.6-49.5 |
GA 32 to 36 weeks | OR 5.0, 95% CI 2.9-8.6 |
Low birth weight |
<1500 g | OR 44.5, 95% CI 35.6-55.5 |
1500 to 2499 g | OR 7.6, 95% CI 6.0-9.7 |
Intrauterine infection |
Any maternal infection during pregnancy | RR 2.5, 95% CI 1.9-3.2 |
Maternal chorioamnionitis | RR 2.9, 95% CI 2.0-4.2 |
Preeclampsia | OR 1.9, 95% CI 1.5-2.5 |
Placental abruption | OR 10.9, 95% CI 8.4-14.1 |
Multiple pregnancy | OR 3.7, 95% CI 3.0-4.5 |
Heavy maternal alcohol consumption | OR 3.3, 95% CI 1.3-8.5 |
Maternal smoking | HR 1.8, 95% CI 1.1-2.9 |
Maternal obesity (prepregnancy BMI ≥30) | RR 1.6, 95% CI 1.1-2.2 |
Small size for gestational age | OR 3.7, 95% CI 3.1-4.4 |
Other congenital abnormalities | OR 5.2, 95% CI 2.8-9.7 |
Apgar <7 at 5 minutes | OR 27.0, 95% CI 23.5-31.2 |
Neonatal infection | OR 14.7, 95% CI 1.7-126.5 |
Respiratory distress syndrome | HR 2.1, 95% CI 1.4-3.1 |
Requiring mechanical ventilation after birth | OR 2.4, 95% CI 2.4-4.5 |
Requiring antibiotic therapy after birth | OR 1.7, 95% CI 1.3-2.2 |
Neonatal seizures | OR 7.4, 95% CI 4.8-11.6 |