Disease process |
Airway obstruction |
Airway obstruction by tumor or by lymphadenopathy |
Bronchoconstriction (COPD, asthma) |
Retained or excess secretions |
Vocal cord paralysis |
Obstructive sleep apnea |
Pulmonary parenchymal |
Widespread tumor metastases |
Pneumonia, aspiration |
Heart failure |
Pericardial disease, tamponade |
Lymphangitic tumor |
Lung resection (eg, lobectomy, pneumonectomy) |
Pneumonitis caused by antineoplastic therapy |
Radiation pneumonitis and fibrosis |
Interstitial lung disease |
Pulmonary vascular |
Venous thromboembolism |
Sinusoidal obstruction syndrome (veno-occlusive disease) |
Tumor thromboembolism |
Pulmonary hypertension |
Superior vena cava syndrome |
Pleural |
Pleural effusion (eg, malignant, drug induced) |
Pleural tumor |
Pneumothorax |
Pleural effusion due to lung entrapment by tumor |
Inspiratory muscle weakness |
Cachexia |
Electrolyte imbalance |
Neuromuscular disease, including paraneoplastic syndromes |
Steroid myopathy |
Diaphragmatic paralysis, phrenic nerve paralysis |
Decreased chest wall compliance |
Restriction post thoracotomy |
Restriction due to advanced chest wall tumor (eg, inflammatory breast cancer) |
Massive ascites |
Massive abdominal organomegaly |
Obesity |
Systemic |
Anemia |
Acidosis |
Arrhythmias |
Neuropsychiatric |
Pain |
Depression |
Anxiety, including hyperventilation |
Respiratory panic |